Expanding Bile Acid Chemical Space: Scalable Synthesis and Derivatisation of a Structurally Novel Bile Acid

Advancing a Sustained Release Form of Penicillin G for the Prevention of Acute Rheumatic Fever and Rheumatic Heart Disease

Engineering an Endophyte-Based Lovastatin Platform: Single-Vector Pathway Reconstruction, In Planta Translation, and Structural Insight into IvrA

Transition-State Analysis of Acid Ceramidase

Synthesis of 4’-Substituted Imino-C-Nucleoside Analogues for use as Antiviral Treatments

Regulation of secondary metabolite biosynthesis in Epichloe festucae

Developing a multidisciplinary pipeline to discover and characterise novel indole diterpene cyclases that generate novel cyclisation structure

Enzyme regulation through reversible hetero-oligomer assembly: the HisZG complex from Staphylococcus aureus

Indole ring decoration in indole terpenoids: characterisation of a novel biosynthetic pathway from Atkinsonella texensis and an investigation of enzyme promiscuity

Drug Design

Drug Design

Drug Design

Drug Development

Drug Design

Molecular Biotechnology

Drug Design

Design and Synthesis of Antiviral Iminoribitol C-Nucleosides

Towards Synthesis of Simplified Analogues of Pateamine A